Spyre Therapeutics, Inc. (SYRE)
NASDAQ · Healthcare
Spyre Therapeutics, Inc. Stock Price History
Spyre Therapeutics, Inc.
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Historical daily closing price for Spyre Therapeutics, Inc. since 2016, adjusted for splits and dividends. The latest closing stock price for Spyre Therapeutics, Inc. as of June 11, 2026 is 76.33.
- The all-time high Spyre Therapeutics, Inc. stock closing price was 299.75 on April 8, 2016.
- The Spyre Therapeutics, Inc. 52-week high stock price is 78.48, which is 2.8% above the current share price.
- The Spyre Therapeutics, Inc. 52-week low stock price is 14.68, which is 80.8% below the current share price.
- The average Spyre Therapeutics, Inc. stock price for the last 52 weeks is 34.45.
Annual Close Price
YEAR-END CLOSE · USD
ANNUAL % CHANGE · %
| Year | Average | Year Open | Year High | Year Low | Year Close | Annual % Change |
|---|---|---|---|---|---|---|
| 2026 | 51.86 | 30.58 | 78.48 | 29.96 | 76.33 | +133.00% |
| 2025 | 19.53 | 23.85 | 34.66 | 11.80 | 32.76 | +40.72% |
| 2024 | 29.97 | 21.40 | 45.37 | 20.41 | 23.28 | +8.18% |
| 2023 | 10.70 | 10.53 | 21.52 | 2.65 | 21.52 | +91.29% |
| 2022 | 37.06 | 119.25 | 119.25 | 8.72 | 11.25 | -90.53% |
| 2021 | 176.37 | 214.00 | 214.25 | 87.50 | 118.75 | -39.64% |
| 2020 | 188.33 | 193.75 | 275.88 | 87.75 | 196.75 | +3.01% |
| 2019 | 192.99 | 201.00 | 235.00 | 152.50 | 191.00 | +2.00% |
| 2018 | 218.52 | 134.50 | 275.00 | 126.75 | 187.25 | +38.45% |
| 2017 | 123.81 | 114.25 | 200.75 | 72.75 | 135.25 | +24.37% |
| 2016 | 158.24 | 244.25 | 299.75 | 99.00 | 108.75 | — |
Spyre Therapeutics, Inc. Stock Price History — FAQ
Spyre Therapeutics, Inc. (SYRE) stock price history — annual and quarterly figures with year-over-year growth and charts.
Where can I see SYRE's stock price history history?
The chart and table above show Spyre Therapeutics, Inc.'s stock price history by year and by quarter, including the growth rate.