Pacific Biosciences of California, Inc. is a biotechnology company that develops, manufactures, and markets advanced DNA sequencing systems for genetic analysis. The company focuses on high-accuracy long-read and complementary short-read sequencing technologies that enable comprehensive characterization of genomes, transcriptomes, and epigenomes. Its product portfolio includes sequencing instruments such as the Revio and Onso systems, along with consumables and software that support end-to-end workflows from sample preparation through data analysis. Pacific Biosciences’ platforms are used by academic and governmental research institutions, pharmaceutical and biotechnology companies, agricultural organizations, and clinical research groups for applications in human genetics, oncology, infectious disease, and plant and animal genomics. The company operates a razor-and-blade business model, generating revenue from both instrument sales and recurring consumable usage. Founded in 2004 and headquartered in Menlo Park, California, Pacific Biosciences plays a notable role in the genomics market by providing tools designed to resolve genetically complex problems and deliver highly detailed views of genetic variation.