# Upstream Bio, Inc. (UPB) — Operating Income

## Annual Operating Income (USD)

| Year | Operating Income |
| --- | --- |
| 2025 | -$160M |
| 2024 | -$78M |
| 2023 | -$40M |

## Quarterly Operating Income (USD)

| Quarter | Operating Income |
| --- | --- |
| 2026-03-31 | -$44M |
| 2025-09-30 | -$38M |
| 2025-06-30 | -$44M |
| 2025-03-31 | -$32M |
| 2024-09-30 | -$19M |
| 2024-06-30 | -$18M |
| 2024-03-31 | -$15M |
| 2023-09-30 | -$9M |

Source: [CompaniesByCap](https://companiesbycap.com/company/UPB/operating-income)